Conditions
Malignant Melanoma
Trial Purpose
Researchers want to learn whether V940 with pembrolizumab can stop advanced melanoma from growing or spreading. Melanoma is a type of skin cancer. Advanced means the cancer has spread to other parts of the body and cannot be removed by surgery. A standard (or usual) treatment for advanced melanoma is immunotherapy. Immunotherapy is a treatment that helps the immune system to fight cancer. V940 is a study treatment designed to help a person’s immune system attack their specific cancer. Pembrolizumab is a form of immunotherapy.
The goal of this study is to learn whether people who receive V940 with pembrolizumab live longer without the cancer growing or spreading than people who receive a placebo with pembrolizumab. A placebo looks like the study treatment, but has no study treatment in it. Using a placebo helps researchers better understand the effects of a study treatment.
NATIONAL TRIAL REFERENCE NUMBER
NCT06961006
EU CT
2023-504923-20-00
When speaking to your doctor or clinical trial representative, please have the trial reference number available.
Resources
Eligibility
Only a qualified healthcare professional can determine if you are eligible to take part in a clinical trial. However, this information may be useful in starting a conversation with your doctor.
Age Range
18+
Sex
All
About The Trial
Trial Phase
Trial Phase 2
Tests the medicine or vaccine in approximately 100 to 500 volunteers. In the case of medicines, volunteers usually have the disease or condition the investigational medicine is designed to treat. In vaccine studies, the volunteers are usually healthy.
Trial start and end dates
- Actual study start date 29 May 2025
- Estimated primary completion date 22 July 2028
- Estimated study completion date 5 September 2031
Trial locations
Locations shown may have changed in some cases. Please call the number listed in the location results to confirm the nearest trial site. Talk with a trial site member for more information.
What can you do next?
If you think this clinical trial might be a good fit and you are interested in taking part, take the next step to see if you are eligible.
Taking part in a clinical trial is an important decision
If you are considering joining a clinical trial, first learn as much as you can about:
- The investigational treatment that is being studied
- What the risks and possible benefits are for participants
Talk to your doctor about the clinical trial before you decide to join.
Read our “What to Consider” page for more questions to ask and think about