Izimo
I-Lymphocytic Leukemia engapheli, I-Lymphocytic Lymphoma encane
Injongo yocwaningo
Umgomo walolu cwaningo ukuhlola i-nemtabrutinib uma kuqhathaniswa nokukhetha komseshi kwe-ibrutinib noma i-acalabrutinib kubahlanganyeli abane-lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) abangazange bathole noma yikuphi ukwelashwa kwangaphambili. Ama-hypotheses ayinhloko ukuthi (1) i-nemtabrutinib ayikho ngaphansi kwe-ibrutinib noma i-acalabrutinib ngokuphathelene nezinga lokuphendula lenjongo (ORR) nge-International Workshop on Chronic Lymphocytic Leukemia (iwCLL) Criteria 2018 by blinded independent central review (BICR) kanye (2) nemtabrutinion i-ibrutinib ekhululekile noma i-ibrutinib ekhululekile ukusinda (PFS) ngokwemibandela ye-iwCLL 2018 yi-BICR.
Isihlonzi se- Clinicaltrials.gov
I-NCT06136559
I-EU CT
2022-501697-19-00
Lapho uxoxa nodokotela wakho noma ilungu leqembu locwaningo lwezokwelapha, sicela ube nenombolo yereferensi yocwaningo noma inombolo ye-EudraCT.
Izinsiza
Ukufaneleka
Uchwepheshe wezempilo uyena kuphela onganquma ukuthi uyafaneleka yini ukubamba iqhaza ocwaningweni lwezokwelapha. Nokho, lolu lwazi lungaba usizo ekuqaleni ingxoxo nodokotela wakho.
Ububanzi Bobudala
18+
Ubulili
Owesilisa/Insikazi
Zonke iziguli ezibhalisela ukuhlola zizothola imithi ngenkathi usocwaningweni.
U-50% uzothola i-nemtabrutinib
U-50% uzothola i-ibrutinib noma i-acalabrutinib
Isigaba socwaningo esiqhubekayo
Isigaba ISIGABA3 Socwaningo
Ezingcwaningweni Zesigaba 3, abacwaningi bazama ukuthola ukuthi umuthi ungasebenza yini enanini elikhulu labantu, ngokuvamile ababambiqhaza abayi-1,000 ukuya ku-5,000 abanesimo sempilo esizokwelashwa umuthi. Ezingcwaningweni zomgomo, ababambiqhaza bangaba abanempilo noma abanezifo noma izimo ezithile. Ucwaningo lwesigaba 3 lungenziwa ehhovisi likadokotela, emtholampilo, noma esibhedlela.
Izinsuku zokuqala nokuqedwa kocwaningo
- Usuku lokuqala kocwaningo Disemba 13, 2023
- Usuku oluyinhloko lokuqeda olulinganiselwe Septhemba 30, 2032
- Usuku lokuqeda ucwaningo olulinganiselwe Septhemba 30, 2032
Izindawo zocwaningo
Izindawo ezibonisiwe kungenzeka zishintshile kwezinye izimo. Sicela ushayele inombolo esohlwini lwemiphumela yendawo ukuqinisekisa isikhungo socwaningo esiseduze. Xoxa nelungu lesikhungo socwaningo ukuthola ulwazi olwengeziwe.
Yikuphi ongakwenza ngokulandelayo?
Uma ucabanga ukuthi lolucwaningo lwezokwelapha lungakulungela futhi unesithakazela sokubamba iqhaza, ukuthatha isinyathelo esilandelayo ukuze ubone ukuthi uyafaneleka yini.
Ukubamba iqhaza ocwaningweni lwezokwelapha kuyisinqumo esibalulekile
Uma ucabangela ukujoyina ucwaningo lwezokwelapha, qala ngokufunda okuningi ngokunokwenzeka ngalo:
- Umuthi wophenyo ocwaningwayo
- Yiziphi izingozi noma izinzuzo ezingaba khona zababambiqhaza
Xoxa nodokotela wakho ngocwaningo lwezokwelapha ungakenzi isinqumo sokujoyina.
Funda ikhasi elithi “Ongakucabangela” ukuthola imibuzo eyengeziwe ongayibuza nongacabanga ngayo