MSD
Ucwaningo Lwezokwelapha
Abacwaningi bafuna izindlela ezintsha zokwelapha izinhlobo zomdlavuza webele ezikulesi simo:
* Oyingozi kakhulu, okusho ukuthi kunethuba eliphakeme kakhulu lokuthi umdlavuza ube mubi nakakhulu noma uphinde ubuye ngemva kokwelashwa
* Osesigabeni sokuqala, okusho ukuthi umdlavuza usebeleni noma ukuma-lymph nodes endaweni ezungeze ibele. Izinhlobo ezi-2 zomdlavuza webele kulolu cwaningo yi-triple-negative breast cancer (TNBC) kanye ne-hormone receptor (HR)-low positive/human epidermal growth factor receptor-2 (HER2) negative breast cancer. Le midlavuza ayinayo noma inezinga elincane lephrotheni ebizwa ngokuthi yi-HER2 kanye namanye amaphrotheni anamathela kumahomoni i-estrogen noma i-progesterone.
I-Sacituzumab tirumotecan (eyaziwa nangokuthi yi-sac-TMT noma MK-2870), umuthi wocwaningo, iwuhlobo lokwelapha oluhlasela ngokuqondile amaseli omdlavuza. Ukwelapha okuhlasela ngokuqondile amaseli omdlavuza, ukwelapha okuzama ukulawula indlela izinhlobo eziqondile zamaseli omdlavuza ezikhula ngayo nezibalala ngayo.
Izinhloso eziyinhloko zalolu cwaningo ukuthola ukuthi abantu abanikezwa i-sac-TMT, i-pembrolizumab, ne-chemotherapy:
* Banamaseli omdlavuza ambalwa yini atholakale ezimileni nakuma-lymph nodes asuswe ngokuhlinzwa uma beqhathaniswa nalabo abanikezwe i-pembrolizumab ne-chemotherapy kuphela
* Baphila isikhathi eside yini ngaphandle kokukhula komdlavuza, ukusabalala kwawo, noma ukubuya kwawo uma beqhathaniswa nalabo abanikezwe i-pembrolizumab ne-chemotherapy kuphela
Isihlonzi se- Clinicaltrials.gov
NCT06966700
I-EU CT
2024-520190-12-00
Lapho uxoxa nodokotela wakho noma ilungu leqembu locwaningo lwezokwelapha, sicela ube nenombolo yereferensi yocwaningo noma inombolo ye-EudraCT.
Uchwepheshe wezempilo uyena kuphela onganquma ukuthi uyafaneleka yini ukubamba iqhaza ocwaningweni lwezokwelapha. Nokho, lolu lwazi lungaba usizo ekuqaleni ingxoxo nodokotela wakho.
Izimo
Isimila Sithonywa Kancane Amahomoni (HR Low-Positive)/Isimila Asinawo Amazinga Aphezulu Ephrotheni Ye-HER2 (HER2-Negative Breast Neoplasms), Izimila Ebeleni (Breast Neoplasms), Umdlavuza Onamandla Onamaseli Antula Ama-Receptor Amathathu (Triple Negative Breast Neoplasms)
Ububanzi Bobudala
18+
Ubulili
Konke
Isigaba socwaningo esiqhubekayo
Ezingcwaningweni Zesigaba 3, abacwaningi bazama ukuthola ukuthi umuthi ungasebenza yini enanini elikhulu labantu, ngokuvamile ababambiqhaza abayi-1,000 ukuya ku-5,000 abanesimo sempilo esizokwelashwa umuthi. Ezingcwaningweni zomgomo, ababambiqhaza bangaba abanempilo noma abanezifo noma izimo ezithile. Ucwaningo lwesigaba 3 lungenziwa ehhovisi likadokotela, emtholampilo, noma esibhedlela.
Izinsuku zokuqala nokuqedwa kocwaningo
Izindawo ezibonisiwe kungenzeka zishintshile kwezinye izimo. Sicela ushayele inombolo esohlwini lwemiphumela yendawo ukuqinisekisa isikhungo socwaningo esiseduze. Xoxa nelungu lesikhungo socwaningo ukuthola ulwazi olwengeziwe.
Uma ucabanga ukuthi lolucwaningo lwezokwelapha lungakulungela futhi unesithakazela sokubamba iqhaza, ukuthatha isinyathelo esilandelayo ukuze ubone ukuthi uyafaneleka yini.
Uma ucabangela ukujoyina ucwaningo lwezokwelapha, qala ngokufunda okuningi ngokunokwenzeka ngalo:
Xoxa nodokotela wakho ngocwaningo lwezokwelapha ungakenzi isinqumo sokujoyina.
Funda ikhasi elithi “Ongakucabangela” ukuthola imibuzo eyengeziwe ongayibuza nongacabanga ngayo